The Canadian Council of Academies provides "...independent, evidence-based, expert assessments that inform public policy development in Canada."
Recent topics covered in their assessments range from regenerative medicine to health product risk communication to medical assistance in dying. Reports can also be used to identify key Canadian data and information sources for a given topic.
A "...leading source for systematic reviews in healthcare". See in particular the linked '(Health) Technology Assessments' and 'Economic Evaluations' databases available underneath the pull-down 'More Resources' tab.
A Canadian non-profit organization, CADTH (Canadian Agency for Drugs and Technologies in Health) provides "...objective evidence to help make informed decisions about the optimal use of health technologies." Covers drugs, diagnostic tests, and medical, dental, and surgical devices and procedures.