Skip to main content
It looks like you're using Internet Explorer 11 or older. This website works best with modern browsers such as the latest versions of Chrome, Firefox, Safari, and Edge. If you continue with this browser, you may see unexpected results.

Research Guides

CHE430: Chemical Plant Design Resources

Primary reference textbook

Other useful books



Books available through HathiTrust (limited time access)


The following books have been digitized by HathiTrust and are currently available for limited access to U of T students, staff, and faculty, via an emergency temporary access service. Instructions for accessing the books are beside the book titles. For more information about HathiTrust, select the following link:  

Useful journals/magazines

Resources required for 2020 projects


Cohort 1           
Tutorial # Industry Project PPSS References
1 Environment Thermal-Carbonization of Wood/Railway Ties
  1. Paul T. Williams, Waste Treatment and Disposal, Chapter 6, “Other Waste Treatment Technologies:  Pyrolysis, Gasification, Combined Pyrolysis-Gasification, Composting, Anaerobic Digestion”, 2nd Ed., John Wiley and Sons Ltd., p.325 
  2. Karl J. Thome-Kozmiensky et al., Waste, 6. Treatment, Ullmann’s Encyclopedia, Wiley-VCH Verlag GmbH & Co. 2012, p.481.
2 Environment Thermal-Carbonization of Organic Municipal Solid Waste
3 Pharma Manufacturing an Anti-inflammatory Drug Candidate
  1. Buon; Christopher, Cantin; Louis-David, Hu; Luo; Xuehong, Tomaszewski; Miroslaw, Imidazopyridine compounds and uses thereof, United States Patent, 9,598,409, April 10, 2018.
4 Specialty Chemicals Polyols for Polyurethanes
  1., accessed July 11, 2020
  2. F. N. Jones, “Alkyd Resins”, Ullman’s Encyclopedia of Industrial Chemistry, Weinheim: Willey-VCH, 2012, DOI: 10.1002/14356007.a01_409
  3. W. Hinz et al., USP 2006/0223973 A1, “Method for Forming a Polyethercarbonate Polyol, October 5, 2006.
5 Specialty Chemicals Reactive Extrusion of Starch
  1. BeMiller J.N., et al., Starch, Ullmann’s, vol. 34, 2012
  2. Xie F. et al., Starch Modifications using Reactive Extrusion, Starch/Stärke, 58 (2006) 131-139.
  3. Wang, S., Li, C., Copeland, L., Niu, Q. & Wang, S. Starch Retrogradation: A Comprehensive Review. Compr. Rev. Food Sci. Food Saf. 14, 568–585 (2015)
  4. Van Der Borght, A., Goesaert, H., Veraverbeke, W. S., & Delcour, J. A. (2005). Fractionation of wheat and wheat flour into starch and gluten: Overview of the main processes and the factors involved. Journal of Cereal Science, 41(3), 221–237.
  5. Mir, S., Manickavasagan, A., & Shah, M. (2019). Whole Grains Processing, Product Development, and Nutritional Aspects. Taylor & Francis.
  6. Wang, S., Li, C., Copeland, L., Niu, Q. & Wang, S. Starch Retrogradation: A Comprehensive Review. Compr. Rev. Food Sci. Food Saf. 14, 568–585 (2015)
  7. Trksak et al., USP 20110124746A1, “Alkenyl succinic acid anhydride half ester emulsifier”, May 26, 2011
  8. Singh, N., & Eckhoff, S. R. (1996). Wet milling of corn - A review of laboratory-scale and pilot plant- scale procedures. Cereal Chemistry, 73(6), 659–667.
  9. Environmental Protection Agency, Corn Wet Milling Emission Factor Documentation, 1994.
6 Specialty Chemicals Batch Modification of Extruded Starch
Cohort 2      
Tutorial # Industry  Project PPSS References
10 Energy  Modification of a Natural Gas Liquid Fractionation Plant
  1. S.M. Thompson et al., Liquefied Petroleum Gas, Ullmann’s Encyclopedia of Industrial Chemistry, 2011 Wiley-VCH Verlag GmbH & Co. KGaaA, Weinham, from:
  2. Technical Manuals:
  3. Koch-Glitch Catalogue and free online software:   
  4. GPSA Handbook: *NB: This book is temporarily available online via HathiTrust. Open the link above and then select the "Get Help" button under the book title. Then follow the prompts to access.*
  5. R. E. Treybal, Mass-Transfer Operations, 3rd edition. New York, NY: McGraw-Hill, 1980.
  6. API 610,  API-520,521,526
11 Energy Ethylene Purification
  1. D. Jeremic, Polyethylene, Ullmann’s Encyclopedia of Industrial Chemistry, 2014 Wiley-VCH Verlag GmbH & Co. KGaA Weinheim, 10.1002/14356007.a21_487.pub3
  2. R. E. Treybal, Mass-Transfer Operations, 3rd edition. New York, NY: McGraw-Hill, 1980.
  3. API 610 (Centrifugal Pumps for Petroleum, Petrochemical and Natural Gas Industries) is identical to ISO 13709:2009 Centrifugal pumps for petroleum, petrochemical and natural gas industries, which we do have access to:
  4. API 520 Part 1 (API Std 520, Sizing, Selection, and Installation of Pressure-relieving Devices, Part I - Sizing and Selection) and API 520 Part 2 (Sizing, Selection, and Installation of Pressure-relieving Devices-Part II, Installation
  5. API 521(Pressure-relieving and Depressuring Systems) – matches with ISO 23251:2019 (Petroleum, petrochemical and natural gas industries - Pressure-relieving and depressuring systems)
  6. API 526 (Flanged Steel Pressure-relief Valves)
12 Energy Biodiesel Plant
  1., accessed June 30, 2020
  2., accessed on June 30, 2020
  3., accessed on June 30, 2020
  4. K. Torzewski, Biodiesel Production, Facts at your Fingertips, Chemical Engineering, Nov 1, 2008.  
13 Environment Tertiary Wastewater Treatment
  2. S. Basu,Controlling Nitrogen and Phosphorous in Wastewater,” CEP, April 2020, p.41.
  3. S.D. Lin and C.C. Lee, Water and Wastewater Calculations Manual, McGraw Hill, 2007.
14 Envrionment Daisy the Digester Demonstration Plant
  1. Nigel G.H. Guilford et al., “Solid-State Anaerobic Digestion of Mixed Organic Waste: The Synergistic Effect of Food Waste Addition on the Destruction of Paper and Cardboard”, Environ. Sci. Technol. 2019, 53, 21, 12677–12687
  2. Nigel G.H. Guilford, M.Eng. Thesis, “A New Technology for Anaerobic Digestion of Organic Waste”, University of Toronto, 2009
  3. Forrestal, B.J. et al., "System and method for the production of biogas and compost”, Canadian Patent 2,468,158, May 23, 2006.
  4. Paul T. Williams, Waste Treatment and Disposal, Chapter 6, “Other Waste Treatment Technologies:  Pyrolysis, Gasification, Combined Pyrolysis-Gasification, Composting, Anaerobic Digestion”, 2nd Ed., John Wiley and Sons Ltd., p.325
  5. Karl J. Thome-Kozmiensky et al., Waste, 6. Treatment, Ullmann’s Encyclopedia, Wiley-VCH Verlag GmbH & Co. 2012, p.481.
  6. Design specs were obtained from the client on June 15, 2020.
  7. Waste Management, Section 22, Perry’s 8th Edition, available as e-book from:
15 Environment Landfill Leachate Treatment Plant
  1. CRRRC, “Capital Region Resource Recovery Centre (CRRRC).” (accessed Jun. 19, 2020).
  2. Environment and Energy, “Landfill standards: A guideline on the regulatory and approval requirements for new or expanding  landfilling sites |,” Government of Ontario, Guidelines, 2010. Accessed: Jun. 19, 2020. [Online]. Available:
  3. M. Pognani, R. Barrena, X. Font, and A. Sánchez, “A complete mass balance of a complex combined anaerobic/aerobic municipal source-separated waste treatment plant,” Waste Manag., vol. 32, no. 5, pp. 799–805, May 2012, doi: 10.1016/j.wasman.2011.12.018.
  4. City of Ottawa, Sewer Use, vol. By-law No. 2003-514. 2003.
  5. Applied Research Foundation, “On-Site Treatment of Landfill Leachate,” Solid Waste Association of North America, Dec. 2014. Accessed: Jun. 19, 2020. [Online]. Available:
16 Pharma Manufacturing Diphtheria Vaccine
  1. D. Lapiska, “An Introduction to Immunity and Vaccines”, CEP, November 2011, p.35
  2. Carabin 2003 - WHO European Region –Seven Key Reasons Why immunization must remain a priority in the WHO European Region
  6. GLOBE NEWSWIRE-- The "Diphtheria, Pertussis, and Tetanus Vaccine Market by Product Type and by End User: Global Opportunity Analysis and Industry Forecast, 2020-2027"
  7. J. A. Aunins et el., Chemical Engineering Perspectives on Vaccine Production”, CEP, Nov 2011, p.37
  8. Bheeman et al., “Process Optimization for Enhanced Production Toxin by Submerged Cultivation of Diphtheria” Journal of Biosciences and Bioengineering, Vol. 91, No. 2, 123-128. 2001
  9. World Health Organization. Global polio eradication initiative. Available at Retrieved 2009 Sep 18.
  10. Toxins (Basel). 2019 Sep 11;11(9). pii: E525. doi: 10.3390/toxins11090525. Vaccine Production to Protect Animals Against Pathogenic Clostridia. Zaragoza NE(1), Orellana CA(1), Moonen GA(2), Moutafis G(2), Marcellin E(3).
  11. Thomassen YE, Rubingh O, Wijffels RH, van der Pol LA, Bakker WA. Improved poliovirus D-antigen yields by application of different Vero cell cultivation methods. Vaccine. 2014;32(24):2782-2788. doi:10.1016/j.vaccine.2014.02.022.
  12. Yvonne E. Thomassen, Aart G. van ’t Oever, Marian Vinke, Arjen Spiekstra, Rene´ H. Wijffels, Leo A. van der Pol, Wilfried A.M. Bakker.; Biotechnology and Bioengineering, Vol. 110, No. 5, May, 2013
  13. R.I Freshney, Animal Cell Culture – a practical approach (chapter 3), IRL Press 1986
  14. Michael Buttler, Animal Cell Culture and Technology, Garland Science 2004, 2nd Edition,  ISBN 1135325375, 9781135325374
  15. Cleaning‐in‐Place: Dairy, Food and Beverage Operations, Third Edition Editor(s): Dr Adnan Tamime 2008 Print ISBN:9781405155038 |Online ISBN:9781444302240 |  Blackwell Publishing Ltd
  16. Agalloco, James. (1990). Steam sterilization-in-place technology. Journal of parenteral science and technology: a publication of the Parenteral Drug Association. 44. 253-6.
17 Pharma Manufacturing Polio Vaccine
18 Hydrometallurgy Lithium Eluate Concentration
  1. U. Wietelmann and M. Steinbuild, “Lithium and Lithium Compounds”, Ullmann’s Encyclopedia of Industrial Chemistry, 2013, Willey-VCH Verlag GmbH & Co. KGaA, Weinheim, 10.1002/14356007.a15_393.pub2
  2. C. H. Cheng et al., International Publication Number WO 2017/039724 A1, March 9, 2017
  3. C.R Marston and M.J. Garska, Process for Selective Adsorption and Recovery of Lithium from Natural and Synthetic Brines, US Patent, 2019/0256368 A1, Aug 22, 2019
19 Hydrometallurgy Hydrochloric Acid Regeneration
  1. A. L. Al-Othman, “Gypsum Production and Hydrochloric Acid Regeneration by Reaction of Calcium Chloride Solution with Sulfuric Acid”, Department of Mining, Metals and Materials Engineering, McGill University, August 2004.
  2.  J. E. Dutrizak and A. Kuiper, The solubility of calcium sulphate in simulated nickel sulphate-chloride processing solutions, Hydrometallurgy, 82, (2006), 13-31
  3. G. Azimi, V.G. Papangelakis, J.E. Dutrizac, “Modelling of calcium sulphate solubility in concentrated multi-component sulphate solutions," Fluid Phase Equilibria 260 (2007) 300-315.


Supplementary resources on specific topics


Green Chemistry and Green Engineering:


  1. Mannan, Sam. (2012). Lees’ Loss Prevention in the Process Industries, Volumes 1-3 - Hazard Identification, Assessment and Control (4th Edition) - 40.2.2 The Twelve Principles of Green Engineering. Elsevier. Retrieved from
  2. Allen, D. T., & Shonnard, D. (2002). Green engineering: Environmentally conscious design of chemical processes. Upper Saddle River, NJ: Prentice Hall PTR.
  3. American Chemical Society (ACS): 12 Principles of Green Chemistry 

 Process Intensification and Reducing Footprint:


  1. Reay, David Ramshaw, Colin Harvey, Adam. (2008). Process Intensification - Engineering for Efficiency, Sustainability and Flexibility. Elsevier. Retrieved from
  2. Klemeš, Jiří Jaromír Varbanov, Petar Sabev Wan Alwi, Sharifah Rafidah Manan, Zainuddin Abdul. (2014). Process Integration and Intensification - Saving Energy, Water and Resources - 1.1 Process Intensification. De Gruyter. Retrieved from


Useful websites

Find other chemistry / engineering related information

Encyclopedias (ebooks)
Chemical / physical properties (ebooks)
Health and safety

Databases for finding research articles and more:

***You must register individually using a computer on campus via the SciFinder Scholar registration page. More information: 
NB: Use your "" e-mail address in order to complete the registration.


Process Simulation Software and Tutorials

Standards, Regulations and Recommended Practice